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molecular oncologySelected PublicationsRICHTER-LARREA JA, ROBLES EF, FRESQUET V, BELTRAN E, RULLAN AJ, AGIRRE X, CALASANZ MJ, PANIZO C, RICHTER JA, HERNANDEZ JM, ROMAN-GOMEZ J, PROSPER F, MARTINEZ-CLIMENT JA. Reversion of epigenetically-mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma. Blood. 2010 Jun 22. [Epub ahead of print] ABSTRACT COURTESY OF PUBMEDMESTRE-ESCORIHUELA C, RUBIO-MOSCARDO F, RICHTER JA, SIEBERT R, CLIMENT J, FRESQUET V, BELTRAN E, AGIRRE X, MARUGAN I, MARÍN M, ROSENWALD A, SUGIMOTO KJ, WHEAT LM, KARRAN EL, GARCÍA JF, SANCHEZ L, PROSPER F, STAUDT LM, PINKEL D, DYER MJ, MARTINEZ-CLIMENT JA. Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood. 2007 Jan 1;109(1):271-80. ABSTRACT COURTESY OF PUBMEDCLIMENT J, DIMITROW P, FRIDLYAND J, PALACIOS J, SIEBERT R, ALBERTSON DG, GRAY JW, PINKEL D, LLUCH A, MARTINEZ-CLIMENT JA. Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer. Cancer Res. 2007 Jan 15;67(2):818-26. ABSTRACT COURTESY OF PUBMEDRUBIO-MOSCARDO F, BLESA D, MESTRE C, SIEBERT R, BALASAS T, BENITO A, ROSENWALD A, CLIMENT J, MARTINEZ JI, SCHILHABEL M, KARRAN EL, GESK S, ESTELLER M, DELEEUW R, STAUDT LM, FERNANDEZ-LUNA JL, PINKEL D, DYER MJ, MARTINEZ-CLIMENT JA. Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes. Blood. 2005 Nov 1;106(9):3214-22. ABSTRACT COURTESY OF PUBMEDRUBIO-MOSCARDO F, CLIMENT J, SIEBERT R, PIRIS MA, MARTÍN-SUBERO JI, NIELÄNDER I, GARCIA-CONDE J, DYER MJ, TEROL MJ, PINKEL D, MARTINEZ-CLIMENT JA. Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome. Blood. 2005 Jun 1;105(11):4445-54. ABSTRACT COURTESY OF PUBMEDMESTRE C, RUBIO-MOSCARDO F, ROSENWALD A, CLIMENT J, DYER MJ, STAUDT L, PINKEL D, SIEBERT R, MARTINEZ-CLIMENT JA. Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays. Leukemia. 2005 Jun;19(6):1082-4. ABSTRACT COURTESY OF PUBMEDDE LEEUW RJ, DAVIES JJ, ROSENWALD A, BEBB G, GASCOYNE RD, DYER MJ, STAUDT LM, MARTINEZ-CLIMENT JA, LAM WL. Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes. Hum Mol Genet. 2004 Sep 1;13(17):1827-37. ABSTRACT COURTESY OF PUBMEDSANCHEZ-IZQUIERDO D, BUCHONNET G, SIEBERT R, GASCOYNE RD, CLIMENT J, KARRAN L, MARIN M, BLESA D, HORSMAN D, ROSENWALD A, STAUDT LM, ALBERTSON DG, DU MQ, YE H, MARYNEN P, GARCIA-CONDE J, PINKEL D, DYER MJ, MARTINEZ-CLIMENT JA. MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma. Blood. 2003 Jun 1;101(11):4539-46. ABSTRACT COURTESY OF PUBMEDMARTINEZ-CLIMENT JA, ALIZADEH AA, SEGRAVES R, BLESA D, RUBIO-MOSCARDO F, ALBERTSON DG, GARCIA-CONDE J, DYER MJ, LEVY R, PINKEL D, LOSSOS IS. Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations. Blood. 2003 Apr 15;101(8):3109-17. ABSTRACT COURTESY OF PUBMEDCLIMENT J, MARTINEZ-CLIMENT JA, BLESA D, GARCIA-BARCHINO MJ, SAEZ R, SÁNCHEZ-IZQUIERDO D, AZAGRA P, LLUCH A, GARCIA-CONDE J. Genomic loss of 18p predicts an adverse clinical outcome in patients with high-risk breast cancer. Clin Cancer Res. 2002 Dec;8(12):3863-9. ABSTRACT COURTESY OF PUBMEDMARTINEZ-CLIMENT JA, VIZCARRA E, SANCHEZ D, BLESA D, MARUGAN I, BENET I, SOLE F, RUBIO-MOSCARDO F, TEROL MJ, CLIMENT J, SARSOTTI E, TORMO M, ANDREU E, SALIDO M, RUIZ MA, PROSPER F, SIEBERT R, DYER MJ, GARCÍA-CONDE J. Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma. Blood. 2001 Dec 1;98(12):3479-82. ABSTRACT COURTESY OF PUBMED |
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