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molecular geneticsSelected PublicationsBANALES JM, GRADILONE SA. Primers on Molecular Pathways - Ion Channels: Key Regulators of Pancreatic Physiology. Pancreatology. 2009 Jul 10;9(5):556-559.
ABSTRACT COURTESY OF PUBMEDBRONCKERS AL, LYARUU DM, JANSEN ID, MEDINA JF, KELLOKUMPU S, HOEBEN KA, GAWENIS LR, OUDE-ELFERINK RP, EVERTS V. Localization and function of the anion exchanger Ae2 in developing teeth and orofacial bone in rodents. J Exp Zool B Mol Dev Evol. 2009 Jun 15;312B(4):375-87. ABSTRACT COURTESY OF PUBMEDBANALES JM, MASYUK TV, GRADILONE SA, MASYUK AI, MEDINA JF, LARUSSO NF. The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD). Hepatology. 2009 Jan;49(1):160-74.
ABSTRACT COURTESY OF PUBMEDBANALES JM, MASYUK TV, BOGERT PS, HUANG BQ, GRADILONE SA, LEE SO, STROOPE AJ, MASYUK AI, MEDINA JF, LARUSSO NF. Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease. Am J Pathol. 2008 Dec;173(6):1637-46. Epub 2008 Nov 6.
ABSTRACT COURTESY OF PUBMEDMASYUK AI, GRADILONE SA, BANALES JM, HUANG BQ, MASYUK TV, LEE SO, SPLINTER PL, STROOPE AJ, LARUSSO NF. Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors. Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G725-34. Epub 2008 Aug 7. ABSTRACT COURTESY OF PUBMEDMARDONES P, MEDINA JF, ELFERINK RP. Activation of cyclic AMP Signaling in Ae2-deficient mouse fibroblasts. J Biol Chem. 2008 May 2;283(18):12146-53. Epub 2008 Mar 4. ABSTRACT COURTESY OF PUBMEDARENAS F, HERVIAS I, ÚRIZ M, JOPLIN R, PRIETO J, MEDINA JF. Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. J Clin Invest. 2008 Feb;118(2):695-709. ABSTRACT COURTESY OF PUBMEDSALAS JT, BANALES JM, SARVIDE S, RECALDE S, FERRER A, URIARTE I, OUDE ELFERINK RPJ, PRIETO J, MEDINA JF. Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis. Gastroenterology. 2008 May;134(5):1482-93. Epub 2008 Feb 14. ABSTRACT COURTESY OF PUBMEDGRADILONE SA, MASYUK AI, SPLINTER PL, BANALES JM, HUANG BQ, TIETZ PS, MASYUK TV, LARUSSO NF. Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19138-43. Epub 2007 Nov 16. ABSTRACT COURTESY OF PUBMEDLYARUU DM, BRONCKERS AL, MULDER L, MARDONES P, MEDINA JF, KELLOKUMPU S, OUDE ELFERINK RP, EVERTS V. The anion exchanger Ae2 is required for enamel maturation in mouse teeth. Matrix Biol. 2008 Mar;27(2):119-27. Epub 2007 Oct 11. ABSTRACT COURTESY OF PUBMED |
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